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The author focus on research topics related to synchrotron-based tomography,
mainly on medical, biomedical, biological, and environmental science imaging
with synchrotron X-rays. Also highlight on nanoscience by utilizing the nanosized
high energy photon beam with light source / accelerator facilities to investigate the
properties of novel biomaterials and nanomaterials and imaging tools for medical,
biomedical, and environmental science imaging research. New and Improved
Tools: Light source / accelerator facilities will provide unprecedented capabilities for
coherence-sensitive approaches, including scanning microscopes and microprobes.
This will reshape the technical choices one would make compared to other facilities,
so that whole-cell tomography would be done with a tenfold reduction in radiation
dose, and chemical state mapping and trace element mapping would be done
with improved sensitivity, spatial resolution, and speed. Extensive and innovative
investigations related to biomaterials and nanomaterials with nanosized high
energy photon beam are valuable. Multi-Technique Integration: Because scientific
questions are often not completely answered by just one technique, an integrated
suite of beamlines ranging from infrared, to soft and hard X-ray, should be developed
with common sample preparation facilities and maximum compatibility of sample
handling and mounting schemes. Cross-Disciplinary Approaches: A significant part
of environmental science today addresses questions of the role of bacterial exudates
and organic coatings on metal and radionuclide transport and reactivity in hydrated
systems, as well as the health effects of contaminants. The overlap between this
area of environmental science and bioimaging involves both scientific insight and
technical approaches, so that this overlap should be embraced.
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