A Short Note on Diabetic dermadromes
DOI: 10.4172/jdce.1000113
Abstract
Diabetic dermadromes are a category of cutaneous disorders that are common in people with diabetes who have had the disease for a long time.
Keywords: cutaneous disorders, gangrene, Beta-carotene
A Short Note On Diabetic Dermadromes
Description
Diabetic dermadromes are a category of cutaneous disorders that are common in people with diabetes who have had the disease for a long time. The following conditions are included in this group:
Gangrene
A lack of blood supply causes gangrene, which is a form of tissue death. A change of skin colour to red or black, numbness, swelling, discomfort, skin breakdown, and coolness are all possible symptoms. The feet and hands are the most frequently affected parts of the body. If the gangrene is caused by an infectious agent, a fever or sepsis may develop.
Signs and symptoms: A change of skin colour to red or black, numbness, discomfort, skin breakdown, and coolness are all possible symptoms. The most popular sites of involvement are the feet and hands.
Causes: A critically inadequate blood supply (e.g., peripheral vascular disease) or infection may cause gangrene. It has been linked to diabetes and long-term tobacco use.
Carotenosis
An accumulation of dietary carotenoids causes an orange discoloration of the outermost skin layer, which is a benign and reversible medical condition. The discoloration is most noticeable in people with light skin and may be mistaken for jaundice. Carotenoids, which include alpha- and beta-carotene, beta-cryptoxanthin, lycopene, lutein, and zeaxanthin, are lipidsoluble compounds. Beta-carotene, lycopene, and lutein are the main serum carotenoids. Carotenoids levels in the blood differ by country, race, and gender in healthy people. All are passively absorbed from the gastrointestinal tract and then partly metabolised to vitamin A in the intestinal mucosa and liver.
Diabetic dermopathy
Diabetic dermopathy is a form of skin lesion that affects people who have diabetes. It starts as small, round, atrophic hyperpigmented papules on the shins and progresses to wellcircumscribed, well-circumscribed, small, round, atrophic hyperpigmented skin lesions. It is the most common of many diabetic skin disorders, with up to 30% of diabetics suffering from it.
Causes: The cause is unclear, but it is believed to be linked to diabetic neuropathy and vascular complications; some speculate that the lesions are more common on the shins, implying a different response to injury. Patients with long-term diabetes and impaired glucose regulation are more likely to develop it.
Malum perforans
Malum perforans is a long-lasting, normally painless ulcer that occurs on the sole of the foot and penetrates deep into or through the skin (in which case it may be called malum perforans pedis). It is a common complication of diabetes mellitus and other nerverelated diseases.
Causes: This condition results from denervation of areas exposed to day-to-day friction of bony prominences. The denervation may be result of any of the following diseases: Spinal injuries, Leprosy, Peripheral nerve injury, Diabetic neuropathy, Tabes dorsalis, Transverse myelitis, Meningomyelocele, Syringomyelia.
Necrobiosis lipoidica
Necrobiosis lipoidica is a necrotizing skin disease that most often affects diabetic patients but may also be linked to rheumatoid arthritis. It's known as necrobiosis lipoidica diabeticorum in the first instance (NLD). NLD affects about 0.3 percent of diabetics, with women accounting for the majority of those affected.
Scleredema
Scleredema is a rare, self-limiting skin condition characterised by gradual thickening and hardening of the skin, which occurs most often on the upper back, neck, shoulders, and face. The skin can also turn red or orange in colour. Scleredema has no clear cause, but it is commonly linked to a disease, such as diabetes, a viral infection, or strep throat.
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