Novel Therapeutic Methods for Evaluating Visceral Adiposity
Received: 26-Nov-2022 / Manuscript No. JOWT-22-83941 / Editor assigned: 28-Nov-2022 / PreQC No. JOWT-22-83941 (PQ) / Reviewed: 12-Dec-2022 / QC No. JOWT-22-83941 / Revised: 16-Dec-2022 / Manuscript No. JOWT-22-83941 (R) / Published Date: 23-Dec-2022 DOI: 10.4172/2165-7904.1000534
Introdution
Adipose tissue distribution anatomically throughout the human body is influenced by age, race, ethnicity, genotype, diet, physical activity, hormone levels, and medication. Ladies, the older and overweight individuals have a higher level of fat tissue. The two primary compartments of body fat tissue are the subcutaneous adipose tissue (SAT) and the visceral adipose tissue (VAT), each with its own metabolic characteristics (VAT). Visceral adiposity has received particular attention due to its connection to a variety of medical conditions [1], despite the fact that all of these tissue types are significant.
In this review, the terms "fat" and "adipose tissue" will be used interchangeably despite their distinct biochemical and metabolic characteristics. Adipose tissue around intra-abdominal organs increases in visceral or central obesity, which is defined as abdominal obesity. Impaired glucose and lipid metabolism, insulin resistance, and an increased risk of colon, breast, and prostate cancer are among the pathological conditions it has been linked to. It has likewise been connected to longer clinic stays, higher paces of contaminations and non-irresistible difficulties, and higher emergency clinic mortality.
Description
The likelihood of developing metabolic syndrome is strongly correlated with the level of obesity. Visceral obesity is a subset of metabolic syndrome that exists on its own. In addition, VAT buildup raises the risk of IHD and arterial hypertension and creates a comprehensive cardiovascular risk profile. Tank discharges bioactive particles and chemicals, for example, adiponectin, leptin, cancer putrefaction factor, resistin and interleutin 6 as a hormonally dynamic tissue (IL-6). Adiponectin is one of these hormones that are particularly important because of its beneficial anti angiogenic effect. Concentrations of adiponectin have been linked to several types of cancer, high blood sugar, hypertension, cardiovascular disease, and Type 2 diabetes. To better comprehend the pathophysiology of diseases associated with obesity in humans, it may be necessary to combine VAT calculations with adiponectin measurements. It is essential to find methods that precisely quantify adipose tissue and can differentiate VAT from total adipose tissue because visceral obesity is linked to a poor prognosis, metabolic abnormalities, and the severity of pathology in a variety of chronic diseases [2].
It is abundantly clear that precise and clinically useful methods are required for estimating VAT. However, it is also essential to develop quantitative criteria for determining visceral obesity in relation to these metabolic abnormalities. These requirements have not yet been precisely defined in any medium. Body mass index (BMI) (weight divided by height squared) provides a cross-sectional area of visceral fat as an accurate and reliable equivalent to visceral fat volume measurement, while CT imaging provides a cross-sectional area of visceral fat as an accurate and reliable equivalent to visceral fat volume measurement are two examples of simple, indirect methods of evaluation for visceral adiposity measurement. On the other hand, specific measures of visceral obesity are required in order to properly classify and define an index of abdominal obesity [3].
Clinically effective procedures
A number of different procedures have been developed for evaluating visceral fat. The most clinically expedient procedures are those that can be carried out quickly, provide immediate benefits, and do not necessitate extensive technical expertise. Bioelectrical impedance analysis (BIA) and anthropometric measurements are intended to provide quick, if insufficient, measurements of body composition; notwithstanding, Tank is just a backhanded gauge when these techniques are utilized. Direct cross-sectional area measurements and volumetric VAT measurements can only be obtained with CT and MRI.
Double energy X-beam absorptiometry: Due to their speed and precision, DXA and air displacement plethysmography, two wholebody imaging techniques, have recently attracted a lot of attention. Despite not always being accessible to clinicians, researchers are increasingly utilizing these modalities. Air dislodging plethysmography is a somewhat new strategy that gauges volume and thickness utilizing pressure-volume relationships. DXA examines the attenuation of two energies emitted by the modality in order to identify fat, lean, and bone mineral content assessments. DXA and air displacement plethysmography, on the other hand, are only able to provide estimates of visceral adiposity because they are unable to distinguish between distinct deposits of adipose tissue.
When compared to intra-abdominal fat measured from DXA and anthropometric data, VAT measurements from single-slice CT scans at the fourth and fifth lumbar vertebrae were found to be incorrect in obese women. In obese women with a higher proportion of upper body fat distribution, it was difficult to distinguish the "narrow" location of the WC on the trunk. The umbilicus circumference, which is located inferior to the waist and is easier to determine despite being larger, is frequently reported in these cases. The legitimacy of the midsection estimation in stout ladies might be hurt because of this variety. Since there are no standard protocols for measuring sagittal diameter and any variation in body posture could affect the measurement value, inconsistency in sagittal diameter measurements is another source of inaccuracy [4].
Ultrasound
Ultrasound is another technique for evaluating fat tissue in the subcutaneous and intra-abdominal areas. A single measurement takes very little time, but it is not very accurate or reproducible. Ultrasonography is not recommended for measuring visceral fat because ultrasound assessments of intra-abdominal adipose tissue have a coefficient of variance of 64 percent. Numerous studies have demonstrated that the value of abdominal ultrasound in detecting intra-abdominal obesity and the quantity of intra-abdominal adipose tissue on CT are correlated well [5].
Conclusion
MRI and CT for quantitatively assessing intra-abdominal adipose tissue, CT and MRI are currently the gold standard. Due to its superior resolution of adipose tissue, CT provides a direct method for measuring visceral fat deposition in both adult and pediatric populations. The essential radiographic measurement used to recognize various tissues is Hounsfield units (HU); between 250 and 30 HU, the window width for identifying fat tissue varies. Voxels are used to measure fat volume, which is then converted to cubic centimeters. Strong fat volume correlations can be obtained by evaluating cross-sectional areas in one or more slices at predetermined landmarks.
Acknowledgement
None
Conflict of Interest
None
References
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- Armellini F, Zamboni M, Rigo L, Todesco T, Bergamo-Andreis IA, et al. (1990) . J Clin Ultrasound 18: 563-567.
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Citation: Simmons AB (2022) Novel Therapeutic Methods for Evaluating Visceral Adiposity. J Obes Weight Loss Ther 12: 534. DOI: 10.4172/2165-7904.1000534
Copyright: © 2022 Simmons AB. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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