天美传媒

Cross shunting; Surgical revascularization; Autologous allograft; Athero-diabetic occlusion; Severe limb ischemia

Introduction

Resection with prosthetics or Aorto-femoral bypass provide an adequate result in such clinical observations and generally stands as the only considerable method of management. These days, most of the endovascular surgeons prefer to perform reconstructive surgeries of iliac arteries, especially in case of distal ischemic purulent-necrotic conditions. In cross-shunting operations the “Crossover” technique has been proven to be a gentler and appropriate aspect of surgery in the treatment of unilateral pathological processes [1].

In the correction of infrainguinal occlusions of the vascular bed of lower extremities in case of atherosclerotic lesions of the arterial pathways, Angioplasty has been the ideal choice of surgical interventions. At the same time, only half of them can perform revascularization surgery. Without surgery, 40% of patients undergo amputation of the lower limb within 6 months after diagnosis, 20% of patients die. To minimalize the catastrophic outcomes of reconstructive surgery of the arteries the following methods which have showed promising results are, the use of modern explants with high rheological properties, the use of autologous shunting material, especially with minimal disintegration and traumatization of the endothelium, implantation of allografts with elements of transplantation techniques [2].

Goals of the study: In order to determine the optimal approach of treatment for the elimination of severe ischemia, especially in the presence of clinically significant trophic disorders, the results of various modern reconstructive techniques used in ilio-femoral-popliteal occlusive lesions of the arteries in the lower extremities were evaluated among patients.

Materials and Methods

Department of Surgical Diseases-I of Grodno University Clinic within the last two years performed, restoration and reconstruction of arterial blood flow in the aorto-femoral segment in 12 patients with gangrenous-ischemic limb trophic disorders categorized as staged IIIIV according to the R.Fontine - A.V.Pokrovsky staging.

During the same period, femoral-popliteal-tibial arterial reconstructions were performed, 56 operated patients with a similar nature of tissue damage. In 50 patients, the occlusive process had an atherosclerotic etiology, and in 18 cases, ischemia was due to atherodiabetic lesions. The age of the patients ranged from 59 to 78 years old, among the operated there were 13 women and 45 men [3, 4].

Results and Discussion

As per the analysis obtained through the above discussed study it was revealed that the choice of the reconstructive methods depends on the patient’s individual conditions. Primarily determined by the presence of an adequate main subcutaneous autogenous vessel, the state of the distal vascular bed during operations below the inguinal ligament, the degree and prevalence of necrotic ischemic tissue damage and somatic status of the patient played a major role in choosing the surgical option in the aorto-ilio-femoral segment [5].

Aorto-femoral bypass operations were performed in 5 patients with occluded aorto-iliac segment and necrotic lesions without perifocal inflammation patients at bifurcation - and 3 patients in linear. In the other 5 patients, prolonged unilateral or segmental obstruction of the aorto-ilio-femoral segment was removed by the original surgical technique of multifocal tunnel de-obliteration. The method of more gentle cross-shunting operations of the “crossover” type turned out to be an expedient and preferred option for choosing surgical treatment for unilateral pathological processes in this segment in 2 patients with a pronounced comorbid status [6, 7].

From the infra-inguinally operated patients with the help of autologous vascular structures, 22 had femoral-popliteal bypass surgery with a reversed vein below the knee joint gap; similar bypass surgery was performed proximally in 8 cases. In 11 patients operated with extended occlusions of the superficial femoral and popliteal arteries, distal anastomosis was super imposed with the tibial arteries below the level of distal obstruction. The restoration of the main blood flow in the popliteal and tibial arteries according to the “in situ” method was carried out in 14 people. In the 1st clinical observation, with the repeated nature of surgical intervention and in the absence of autologous material during bypass surgery in the femoral-popliteal position, an arterial allograft with elements of graft technology was successfully transplanted [8, 9].

In the early postoperative period, 5 of the operated patients developed complications that required repeated surgical interventions the 1st - bleeding from the anastomosis, in the 4th-thrombosis. In 2 patients, adequate revascularization of the limb was not achieved and amputation was performed. A limb with positive dynamics in a functional state was preserved in 97.1% [10-12].

Conclusion

Hence, with regards to aforementioned validation of the study, the use of autogenous venous material, modern original de-obliterating reconstructions of arterial vasculature and transplantable allograft structures may be promising in the amelioration of occlusive pathology in severe life threatening lower limb ischemia in the stage of trophic disorders.

Conflict of Interest

None

Acknowledgement

None

1. Russu E, Mureșan V, Arbănași EM, Kaller R, Hosu I, et al. (2022) .J Clin Med. 11: 26-30.

, ,

2. Muresan, Cosarca VA, Russu MC, Niculescu E, Soimu R, et al.(2021) (CLI) J Interdiscip Med 6: 108–111.

, ,

3. Russu, Eliza, Adrian Vasile Mureșan, Daniela Elena Nedelea, Raluca Niculescu, et al. (2023) .Int J Environ Res Public Health20: 212-220.

, ,

4. Shu J, Santulli G (2018) . Atherosclerosis. 275: 379-381.

, ,

5. Conte MS, Bradbury AW, Kolh P, White JV, Dick F, et al.(2019) . J Vasc Surg 69: 3-125.

, ,

6. Panigada M, Bottino N, Tagliabue P (2020) . J Thromb 18: 1738-1742.

, ,

7. Giannis D, Ziogas IA, Gianni P (2020) . J Clin Virol 127: 104-105.

, ,

8. Harrison SL, Fazio-Eynullayeva E, Lane DA, Underhill P, Lip GYH (2020) . PLoS Medicine 17-106-109.

, ,

9. Dye TD, Bogale S, Hobden C, Tilahun Y, Deressa T, et al. (2011) . Int J Cancer 5: 2012-2015.

, ,

10. Anderson BO, Shyyan R, Eniu A, Smith R, Yip CH, et al. (2006) . Breast J 12: 12-15.

, ,

11. Chow, Loh, Wong, Cheng, Fung, et al. (2007) . Public Health Nurs 24: 125-128.

, ,

12. Bener, Ayoubi, Moore, Basha, Joseph, et al. (2009) . Asian Pac J Cancer 10: 599-604.

, ,