A Pilot Study of Induction Triplet Chemotherapy Followed by Minimally Invasive Surgery for Stage 3-4 Resectable Oropharyngeal Cancer
Received Date: Apr 10, 2015 / Accepted Date: May 19, 2015 / Published Date: May 26, 2015
Abstract
The current study reports the results of an open label pilot study evaluating a novel treatment protocol for patients with locally advanced head and neck cancer. Patients received induction chemotherapy and those who had a clinical complete response to induction chemotherapy were offered trans-oral nidusectomy for the primary lesion and neck node dissection. If a pathologic complete response was achieved, patients were then observed. Patients not achieving a clinical or pathologic complete response to induction therapy were subsequently treated with chemoradiation.
Keywords: Induction, Head and neck cancer, Chemotherapy
Citation: Rao K, Robinson K, Malone J, Clausen C, Shevlin B, et al (2015) A Pilot Study of Induction Triplet Chemotherapy Followed by Minimally Invasive Surgery for Stage 3-4 Resectable Oropharyngeal Cancer . Otolaryngol (Sunnyvale) 5: 196. Doi: 10.4172/2161-119X.1000196
Copyright: © 2015 Rao K, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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