A Purification Protocol for Escalating the Sensitivity of Mass Spectrometry Dependent innovative Protein Determination in Human Chorionic Villi
Received Date: Nov 03, 2022 / Accepted Date: Nov 27, 2022 / Published Date: Nov 28, 2022
Abstract
Recently plenty of success has been done regarding acquisition of mass spectrometric isolation of differentially controlled proteins along with invention of newer proteins, biomarkers, protein modifications as well as polymorphisms in different human tissues [1]. However, hurdles continue regarding the assessment in addition to evaluation of properties of proteins existent in lesser quantities inclusive of, corroborating what are known as the ‘’missing proteins’’.A missing protein implies a nonverified genetic sequencing regarding which a protein has not been found till date [2].As per the International Human Proteome Project(HUPO),at present1343 missing proteins without any function assigned exist, either anticipated by bioinformatics assessment or by experimental evaluation. The problems encountered regarding estimation of the missing proteins might be associated with their lesser quantities in numerous tissues besides getting expressed in just occasional cell kinds in the human body.
Citation: Kaur KK, Dr. Allahbadia GNK, Singh M (2022) A Purification Protocol for Escalating the Sensitivity of Mass Spectrometry Dependent Innovative Protein Determination in Human Chorionic Villi. J Anal Bioanal Tech 13: 486.
Copyright: © 2022 Kaur KK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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