Benzimidazoles - A Promising Lead for Antipyschotic Drug Design
Received Date: Jun 03, 2022 / Published Date: Jun 30, 2022
Abstract
Benzimidazole is outstandingly effective compounds and there are a number of reviews available for biochemical and pharmacological studies which confirmed that these molecules are useful. This review presents a comprehensive overview on selected synthetic routes towards antipsychotic drug containing benzimidazole as published in both journal and patent literature. Owing to the vast number of potential structures, we have concentrated only on antipsychotic drugs containing benzimidazole and focused principally on the assembly of the heterocyclic core. In order to target on benzimidazole this is most representative chemical entities. Researchers around the world are paying greater attention to and showing increasing interests in this field. However, challenges such as drug resistance, relatively little knowledge of structure of receptors and rare convenient methods for synthesis of benzimidazoles still exist. We hope this review will form a comprehensive foundation and reference source that will open up new opportunities for researchers interested in benzimidazole containing antipsychotic agents and drug designing.
Citation: Kankate RS, Wagh DD, Kshirsagar SJ (2022) Benzimidazoles - A Promising Lead for Antipyschotic Drug Design. J Anal Bioanal Tech 10: 465. Doi: 10.4172/2155-9872.1000466
Copyright: © 2022 Kankate RS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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