天美传媒

Abstract

Method validation is a crucial process in analytical chemistry, ensuring that methodologies yield reliable and accurate results. With the rapid advancement of analytical techniques, it is essential to evaluate new methods against established standards to maintain data integrity and regulatory compliance. This article explores the principles of comparative method validation, emphasizing the importance of rigorous evaluation in ensuring method performance. The methodology section details various approaches for comparative validation, including statistical analysis, robustness testing, and proficiency testing. The discussion highlights the benefits and challenges of adopting new methods, the role of regulatory frameworks, and the impact of technological advancements. The article concludes with recommendations for best practices in comparative method validation to foster innovation while ensuring quality and reliability in analytical results.