天美传媒

Abstract

Hyperglycemia, characterized by elevated blood glucose levels, is a hallmark of diabetes mellitus and can also occur in various other conditions. This abstract delves into the multifaceted aspects of hyperglycemia, elucidating its underlying mechanisms, clinical manifestations, and far-reaching consequences on health. Firstly, the abstract addresses the pathophysiology of hyperglycemia, emphasizing insulin resistance, impaired insulin secretion, and aberrant glucose metabolism. It explores how dysregulation in these processes leads to sustained elevation of blood glucose levels, contributing to chronic complications.

Secondly, the abstract highlights the clinical manifestations of hyperglycemia, ranging from subtle symptoms such as increased thirst and frequent urination to more severe outcomes including diabetic ketoacidosis and hyperosmolar hyperglycemic state. It underscores the importance of early recognition and management to mitigate acute and chronic complications. Furthermore, the abstract discusses the systemic impact of hyperglycemia on various organ systems, including the cardiovascular, renal, neurological, and ocular systems. It underscores how prolonged exposure to elevated glucose levels can culminate in macrovascular complications such as coronary artery disease and microvascular complications such as diabetic nephropathy and retinopathy. Moreover, the abstract elucidates the bidirectional relationship between hyperglycemia and inflammation, oxidative stress, and endothelial dysfunction, perpetuating a vicious cycle of tissue damage and impaired healing.