Extracellular Vesicles for Drug Delivery: Interactions and Pharmacokinetic Insights
Received Date: Jun 01, 2024 / Published Date: Jun 27, 2024
Abstract
Extracellular vesicles (EVs), including exosomes and microvesicles, have emerged as promising vehicles for drug delivery due to their natural ability to transport bioactive molecules between cells. This abstract provides an overview of EVs as drug delivery systems, focusing on their interactions with target cells and elucidating their pharmacokinetic characteristics. We discuss the biogenesis and composition of EVs, highlighting their capacity to encapsulate diverse cargoes including proteins, lipids, and nucleic acids. Insights into EV-mediated cellular uptake mechanisms, biodistribution in vivo, and clearance pathways are examined, underscoring their potential applications in improving drug delivery efficiency and therapeutic outcomes across various disease models. The integration of EVs into pharmacological strategies represents a transformative approach towards personalized medicine, offering novel insights and opportunities for targeted therapy development.
Citation: Victoria R (2024) Extracellular Vesicles for Drug Delivery: Interactionsand Pharmacokinetic Insights. J Cell Mol Pharmacol 8: 218.
Copyright: © 2024 Victoria R. This is an open-access article distributed under theterms of the Creative Commons Attribution License, which permits unrestricteduse, distribution, and reproduction in any medium, provided the original author andsource are credited.
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