天美传媒

Abstract

Gene editing technologies have revolutionized pharmacological interventions by enabling precise modifications to the genome, offering new avenues for treating genetic disorders and advancing drug discovery. This abstract explores key gene editing tools such as CRISPR-Cas9, TALENs, and zinc finger nucleases, emphasizing their mechanisms and applications in pharmacology. Applications include therapeutic genome editing to correct disease-causing mutations, engineering cells for drug delivery, and enhancing drug efficacy through targeted modifications. Ethical considerations regarding safety, off-target effects, and regulatory challenges are discussed, highlighting the need for rigorous oversight and ethical guidelines. Future directions focus on advancing precision medicine through personalized gene therapies and integrating gene editing with other therapeutic modalities. Keywords: Gene Editing, CRISPR-Cas9, Pharmacology, Therapeutic Genome Editing, Drug Discovery

Gene editing technologies have emerged as transformative tools in biomedical research, offering unprecedented precision and versatility in modifying genetic material. These technologies hold immense promise for revolutionizing pharmacological interventions by enabling targeted modifications to correct genetic mutations, engineer therapeutic proteins, and enhance drug discovery and development processes. This article explores the evolution of gene editing technologies, their applications in pharmacology, ethical considerations, regulatory challenges, and future directions in harnessing these technologies for advancing precision medicine.