Past, Present and Future in Two-Dimensional Liquid Chromatography: A Comprehensive Review
Received Date: Aug 03, 2022 / Published Date: Aug 30, 2022
Abstract
The purpose of this overview is to illustrate the history of 2D liquid chromatography, as well as the concepts that underpin it and the ongoing questions it faces. In the qualification and quantification of closely eluting analytes, two-dimensional liquid chromatography is an analytical tool. Many approaches, such as heart cutting technology, have transformed analyte selection in complicated biological mixtures. Multiple heart-cutting, which uses multiple sampling loops, provides multiple peak samples from the first-dimensional analysis without jeopardizing the temporary overlap of second-dimensional analysis.
Citation: Uma Shankar MS, Basappa P (2022) Past, Present and Future in Two- Dimensional Liquid Chromatography: A Comprehensive Review. J Anal Bioanal Tech 13: 476.
Copyright: © 2022 Uma Shankar MS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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