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World Journal of Pharmacology and Toxicology
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  • World J Pharmacol Toxicol ,

The Effectiveness of Various Brands of the Drugs Fenbendazole and Ivermectin in Treating Horses with Strongyle Nematodes in Holeta, Oromia, Central Ethiopia

Haben Fesseha Gebremeskel1 and Isayas Asefa Kebede2*
1School of Veterinary Medicine, Wolaita Sodo University, Ethiopia
2School of Veterinary Medicine, Ambo University, Ethiopia
*Corresponding Author : Isayas Asefa Kebede, School of Veterinary Medicine, Ambo University, Ethiopia, Email: isayasasefa@ambou.edu.et

Received Date: Mar 04, 2024 / Accepted Date: Mar 29, 2024 / Published Date: Mar 29, 2024

Abstract

Background: Gastrointestinal parasites have always been a problem, and they are likely to continue to be a longterm issue that threatens the livestock industry.

Methods: The purpose of this study was to assess the efficacy of various Fenbendazole and Lvermectin brands against strongyle nematodes in naturally infected horses in Holeta, central Ethiopia. A total of 120 horses were divided into three groups at random. Group 1 horses were left untreated (n=12), while Group 2 horses were given five different brands of Ivermectin (Sg-ivermectin 1%, Tecmectin, Ivertong, Ivermectin 1%, Ivervik 1%), and Group 3 horses were given four different brands of Fenbendazole (Fenbendazole, Fenacure 750mg, hunter 22%, Fenacure 22%). Fecal samples were collected rectally and parasitological processed using the modified McMaster method and fecal culture, respectively, to determine Egg Per Gram (EPG) and strongyle species. The efficacy of these Anthelmintics was determined by comparing the EPG before (day 0) and after treatment using a Fecal Egg Count Reduction Tests (FECRT) (day 14).

Results: The results of this study revealed that the efficacy of Ivermectin brands was superior to that of fenbendazole brands. Horses treated with Ivervik 1%, Hunter 22%, SG-Ivermectin 1%, Tecmectin, Ivertong, and Fenacure 22% had the highest reduction in fecal egg counts, followed by horses treated with Fenbendazole, Ivermectin 1%, and Fenacure 750 mg. Strongyle spp. and P. equorum were the most common strongyle species in the study area’s horses.

Conclusion: This field study found that the various tested brands of Ivermectin and Fenbendazole were effective against Strongyle spp. and P. equorum in horses.

Citation: Gebremeskel HF, Kebede IA (2024) The Effectiveness of Various Brandsof the Drugs Fenbendazole and Ivermectin in Treating Horses with StrongyleNematodes in Holeta, Oromia, Central Ethiopia. World J Pharmacol Toxicol 7: 235.

Copyright: © 2024 Gebremeskel HF, et al. This is an open-access articledistributed under the terms of the Creative Commons Attribution License, whichpermits unrestricted use, distribution, and reproduction in any medium, providedthe original author and source are credited.

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