天美传媒

Abstract

Immunoassays play a critical role in the drug development process, facilitating the discovery and validation of biomarkers, as well as enabling therapeutic monitoring in clinical settings. These assays utilize the specificity of antibodies to detect and quantify target molecules, providing essential data throughout various stages of drug development. This article provides an overview of the applications of immunoassays in biomarker discovery, pharmacokinetics, and therapeutic drug monitoring. The methodology section details different immunoassay techniques, including enzymelinked immunosorbent assays (ELISA), radioimmunoassays (RIA), and newer multiplex assays. The discussion highlights the challenges and limitations faced in the application of immunoassays, such as specificity, sensitivity, and regulatory compliance. Finally, the future directions of immunoassays in drug development are explored, emphasizing the potential for innovation and improved patient outcomes.