PhD Studentship - Combining functional electrical stimulation and spinal stimulation to optimise walking in people with Multiple Sclerosis, a feasibility study

Electrical stimulation, specifically functional electrical stimulation (FES) has been used in clinical practice for over 25Ìýyears to support rehabilitation for people with upper motor neuron conditions such as Multiple Sclerosis (MS), stroke andÌýspinal cord injury (SCI). FES is effective through small electrical impulses to activate weak or paralysed muscles throughÌýexciting the nerves that connect to the muscles. It is most frequently administered through self-adhesive patches orÌýelectrodes which are placed on the surface of the skin directly above the muscle. The electrical stimulation can be usedÌýduring functional activities such as walking, reaching or cycling to help enhance the muscle contraction or motor control.ÌýSurface spinal stimulation works in the same way as FES, electrical impulses administered through sticky pads toÌýelectrodes. However, the target area of stimulation is the spine/spinal cord at the level of the nerve root of the weakenedÌýmuscle.Ìý

Clinician’s and researchers are continuing to understand the underlying mechanisms of how electrical stimulation worksÌýand its impact on neuroplasticity. Neurophysiological techniques such as functional magnetic resonance imaging (fMRI)Ìýand transcranial magnetic stimulation (TMS) have been used to establish neurophysiological changes because of usingÌýFES technologies, these techniques are not often used alongside behavioural measures and patient reported outcomes.Ìý

The aim of this interesting and novel project is to explore electrical stimulation in more depth to better understand howÌýstimulation can contribute to improved function for people with MS.ÌýThe successful applicant will work with the research team to develop the project and research methodology providing andÌýexciting opportunity to develop and shape the research in this area.

This is a fully-funded PhD studentship which includes a stipend of £18,622 each year to support your living costs.Ìý

Key information

Next start date:

27 January 2025

Location:

ÌìÃÀ´«Ã½, Lansdowne Campus

Duration:

36 months

Entry requirements:

Outstanding academic potential as measured normally by either a 1st class honours degree or equivalent Grade Point Average (GPA), or a Master’s degree with distinction or equivalent. If English is not your first language you'll need IELTS (Academic) score of 6.5 minimum (with a minimum 6.0 in each component, or equivalent). For more information check out ourÌýfull entry requirements.Ìý