Case Report
[18F]-Fdg Pet Identified Superior Colliculi Hypometabolism in Progressive Supranuclear Palsy
Alice Jaillard1*, Grégory Petyt1, Maxime Morelle1, Caroline Moreau2,3 and Franck Semah1,31CHU Lille, Nuclear Medicine Department, F-59000 Lille, France
2CHU Lille, Neurology Department, F-59000 Lille, France
3Inserm, U1171, F-59000 Lille, France
- *Corresponding Author:
- Alice Jaillard
Service de médecine nucléaire et Imagerie fonctionnelle
Hôpital Roger Salengro- Centre Hospitalier Régional Universitaire de Lille
2 avenue Oscar Lambret-59037 Lille Cedex, France
Tel: 0033 20445656
E-mail: alice.jaillard@gmail.com
Received date: July 18, 2016; Accepted date: October 24, 2016; Published date: October 31, 2016
Citation: Jaillard A, Petyt G, Morelle M, Moreau C, Semah F (2016) [18F]-Fdg Pet Identified Superior Colliculi Hypometabolism in Progressive Supranuclear Palsy. J Alzheimers Dis Parkinsonism 6:278. doi:10.4172/2161-0460.1000278
Copyright: ©2016 Jaillard A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Hypometabolism in the fronto-mesial cortex and in the anterior cingulate cortex were reported in patients with progressive supranuclear palsy (PSP). Severe neuronal loss, associated with gliosis and neurofibrillary tangles were reported in the superior colliculi of patients with PSP in the initial clinico-neuropathological description of the disease by Steele, Richardson and Olszewski. Nowadays, high-resolution positron emission tomography with [fluorine-18] fluoro-D-glucose (18F-FDG PET) with magnetic resonance (MR) image fusion can reveal hypometabolism in the superior colliculi in patients with PSP.
