Research Article
UV-Visible Spectrophotometric Method Development and Validation of Assay of Paracetamol Tablet Formulation
Siladitya Behera*, Subhajit Ghanty, Fahad Ahmad, Saayak Santra, and Sritoma Banerjee
Department of Quality Assurance and Pharma Regulatory Affairs, Gupta College of Technological Sciences, West Bengal, India
- *Corresponding Author:
- Siladitya Behera
Department of Quality Assurance and Pharma Regulatory Affairs
Gupta College Of Technological Sciences
Ashram More, G.T.Road
Asanol-713301, Burdwan District
West Bengal, India
E-mail: Siladitya.behera@gmail.com
Received date: October 01, 2012; Accepted date: October 27, 2012; Published date: October 31, 2012
Citation: Behera S, Ghanty S, Ahmad F, Santra S, Banerjee S (2012) UV-Visible Spectrophotometric Method Development and Validation of Assay of Paracetamol Tablet Formulation. J Anal Bioanal Tech 3:151. doi: 10.4172/2155-9872.1000151
Copyright: © 2012 Behera S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
A novel,safe and sensitive method of spectrophotometric estimation in UV-region has been developed for the assay of Paracetamol in its tablet formulation. The method have been developed and validated for the assay of Paracetamol using Methanol and water as diluents. Which does not shows any interference in spectrophotometric estimations. All the parameters of the analysis were chosen according to ICH [Q2(R1)] guideline and validated statistically using RSD and %RSD along with neat chromate grams.
