天美传媒

Abstract

Background and Aim: The aim of the present study is to assess the association of coronary risk factors with glucose levels among patients with type-2 diabetes mellitus. Subjects and Methods: This study included 270 subjects with type 2 diabetes mellitus. We obtained primary risk factors, disease history, anthropometry, blood pressure, blood glucose and lipids by questionnaires following WHO guidelines and laboratory data by standard methods. Results: Of 270 patients with type 2 diabetes, 43 percent of males and 50 percent of females are having family history of diabetes mellitus. None of the subjects fall in malnutrition category whereas, 30 percent were normal weight, 50 percent were overweight and 18 to 30 percent were obese. The risk factor prevalence rates are: systolic hypertension; 40%, diastolic hypertension; 60%, hypertriglyceridemia; 55-60% and hypercholesterolemia; 32-37%. Both fasting blood glucose (FBS) and post prandial blood glucose (PPBS) levels increased from<39 yrs age group to 40-54 yrs age group and then decreased in >55 yrs age group (p<0.05). Blood glucose levels were unaltered within the categories of BMI, while WHR elevated the FBS levels (p<0.05). Both FBS and PPBS elevated from latent diabetics to diabetics with 5-9 yrs duration, there after a decrease was observed in FBS alone. Sixty percent of the variance in FBS levels and 58 percent of the variance in PPBS was explained by independent variables. The ODD?s of FBS are: 40-54 yrs age group (1.023, 95% CI: 1.011-1.034), >55 yrs (1.020, 95% CI: 1.009-1.032), duration of diabetes for 5-9 yrs (1.024, 95% CI:1.010-1.039), family history (1.084, 95% CI: 1.063-1.106), WHR>1 (1.028, 95% CI: 1.006-1.050), systolic hypertension (1.023, 95% CI:1.016-1.030), diastolic hypertension (1.022, 95% CI: 1.015-1.030). Similar ODD?s were obtained for PPBS levels also. Conclusion: In conclusion the results indicate that family history, duration of the disease and blood pressure are significant risk factors in type-2 diabetes mellitus. Hence preventive strategies warranted towards the management of hyperglycemia in type 2 diabetes to prevent vascular disease.

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