Journal of Obesity & Weight Loss Therapy
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Can insulin-like growth factor-1 (IGF-1) predict menstrual recovery in adolescents with anorexia nervosa (AN)?
17th International Conference on Obesity, Diet and Nutrition
Vasileios Karountzos, Pandelis Tsimaris, Artemis Tsitsika, Flora Bacopoulou, George Panotopoulos, Nikolaos Athanasopoulos, Anastasia Vatopoulou,Aikaterini Giannouli, Konstantinos Panoulis and Efthimios K Deligeoroglou
Aretaieion Hospital, GreeceNational and Kapodistrian University, GreeceAghia Sophia Childrens Hospital, GreeceAristotle University of Thessaloniki, GreeceP & A Kyriakou Childrens Hospital, Greece
Posters & Accepted Abstracts: J Obes Weight Loss Ther
DOI:
Abstract
Aim: The aim of this study was to assess whether insulin-like growth factor-1 (IGF-1) can be a good predictor of menstrual recovery in girls with anorexia nervosa (AN). Material & Methods: Prospective study of adolescents presented with anorexia nervosa (AN) and amenorrhea in our department. Anthropometric parameters, luteinizing hormone (LH), estradiol and IGF-1 levels were evaluated at the beginning and at the time of menstrual recovery, while all girls were being treated for nutritional recovery. Results: Thirty eight adolescents with mean age 17.23卤0.89 years, mean body mass index 16.67卤2.46 Kg/m2, mean waist-hip ratio 0.77卤0.12, mean waist circumference 0.67卤0.09 m, mean LH 0.18卤0.03 (IU/L), mean estradiol levels 23.46卤5.77 pg/ml and mean IGF-1 levels 126.56卤23.77 ng/ml, were included in our study. Mean years of menstrual recovery were 2.76卤0.62. All hormonal profiles improved after resumption of menses and nutritional recovery, with IGF-1 correlating the most (p<0.0001), showing mean levels of 327.78卤56.12 ng/ml. Conclusions: IGF-1 plays a crucial role as a predictor of menstrual recovery, although there is a big list of other hormonal and anthropometric factors that should not be omitted during the evaluation and management of girls with AN.Biography
E-mail: vasiliskar1985@yahoo.com
