天美传媒

Abstract

Introduction: Dentists have considered chlorhexidine as the gold standard antimicrobial solution against oral microbes for decades. The side effects of chlorhexidine and our historical reliance on natural remedies create the need for herbal alternatives. This study evaluated the effectiveness of chlorhexidine, coconut oil, and moringa on the prevalence of human oral bacteria using a singleblind, randomized clinical trial method. Methods: A total of 90 oral swabs were collected from consenting human participants on day 0 of the clinical trial. The participants were given either chlorhexidine (group A), coconut oil (group B), or Moringa oleifera (group C) mouthwashes and instructed to rinse for 14 days, twice daily. The participants were sampled again on day 14. Total plate count (TPC) and differential plate count (DPC) were done on both samples of each participant collected on day 0 and day 14. Standard biochemical tests identified bacteria. Results: Streptococcus mitis, Veillonella parvula, Klebsiella aerogenes, Streptococcus mutans, Bacteroides fragilis, Aggregatibacter actinomycetecomitans, Streptococcus pneumoniae, and Staphylococcus aureus were isolated from the plaque. All 3 types of mouthwash exhibited statistically significant differences in TPC and DPC of day 0 and day 14 when compared using a paired t-test (P value = 0.03, 0.01, and < 0.01, respectively). No statistically significant difference was noted in the antimicrobial activity of the three types of mouthwash when compared using oneway ANOVA, posthoc Tukey鈥檚 test. Conclusion: Our results show that M. oleifera and coconut oil have a bactericidal effect on oral microbial populations associated with caries and periodontal disease, comparable to chlorhexidine..

Biography

Abu Bakar Shoukat works at Department of Microbiology, Quaid-e-Azam University, Islamabad, Pakistan.