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Abstract

It is recognized that physical activity has influence on plasma glucose concentrations, mainly due to increased insulin sensitivity and described the effect can persist for up to 48 hours after performing the physical activity; however, so far its effect is not known on glycemic variability. A quasi-experimental study was carry out in 23 sedentary subjects of 30 to 40 years with a normal or obesity body mass index with normal glucose tolerance was. After signing the written informed consent, we perform a continuous ambulatory monitoring of glucose every 5 minutes for 96 hours using a monitor iPro2 (Medtronic , Northridge , CA). The first two days of the study all participants were instructed to follow the normal sedentary life style and for the next two days to perform 30 minutes of moderate intensity physical activity (60 to 70% of maximum heart rate). The glycemic variability was calculated by the mean amplitude of glycemic excursions (MAGE), mean of daily differences (MODD) and area under the curve of glucose (AUCG). Statistical significance: p<0.05. Ethics committee approval: CEI/172/2015. Clinical trials registration: NCT02620670. All participants signed the informed consent. Preliminary results: the mean for age of normal and obesity group was 32.5�±3.1 and 34.4�±3.4 years respectively. The AUC of glucose for the first day in the normal group was 7468.80�±806.54 and 8097.19�±722.82 mmol*h/l for obesity group; the AUC in the second day of physical activity was 7047.18�±2304.47 and 7215.24�±2036.60 mmol*h/l respectively. We observed differences between groups, and comparing before and after activity.

Biography

Email: lizet.rosales@gmail.com