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Prevalence of UMOD gene mutation among Saudi patients with kidney failure
3rd Annual Congress on Infectious Diseases
Saleh Ahmed Alogla,Hussain Gadelkarim Ahmed, Rayan Mohsen Ismael, Abdulkarim Ali Alqufayi, Saleh Othman Alamer, Hamoud Khalid Alshaya, Ibrahim Abdelmageed Ginawi and Awdah M Al-hazimi
University of Hail, KSA King Abdul-Aziz University, KSA
ScientificTracks Abstracts: J Infect Dis Ther
DOI:
Abstract
Background: Mutations in the uromodulin (UMOD) gene lead to a dominant hereditary renal disease, which may ultimately result in kidney failure. Therefore, the aim of this study was to assess the burden of UMOD associated renal among Saudi patients with renal failure (RF). Methodology: PCR amplification of 10 exons (forward and reverse) enclosed in the UMOD gene is done on the patient's genomic DNA of 103 Saudi patients with RF. Results: Of the 103 patients, UMOD gene mutation was identified in 10/103 (9.7%). v UMOD gene mutation is relatively prevalent among Saudi patients with RF. Further evaluation of different mutations in this gene is important for overall assessment of its role in RF among Saudi population.Biography
Saleh Ahmed Alogla present is a student of Medical college in University of Hail, Saudi Arabia.
